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Face Transplant Research


 

Scientific Publications

Overview

Technical-Surgical

Immunological

Psychosocial and Ethical 

 

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Scientific & Lay Presentations


Scientific Publications

Overview Articles (Face and Hand Transplantation)

Our Work:

Barker, J. H., Stamos, N., Furr, A., et al. Research and events leading to facial transplantation. Clin Plast Surg 34: 233-250, 2007.

Brown, C. S., Gander, B., Cunningham, M., Furr, A., Vasilic, D., Wiggins, O., Banis, J. C., Vossen, M., Maldonado, C., Perez-Abadia, G., Barker, J. H. Ethical considerations in face transplantation. Int J Surg 5: 353-364, 2007.

Gazarian, A., Abrahamyan, D. O., Petruzzo, P., Kanitakis, J., Guigal, V., Garret, J., Rizzo, C., Durand, P. Y., Fredenucci, J. F., Streichenberger, T., Parmentier, H., Galewicz, T., Guillot, M., Sirigu, A., Burloux, G., Morelon, E., Braye, F., Badet, L., Martin, X., Dubernard, J. M., Eljaafari, A. [Hand allografts: experience from Lyon team.]. Ann Chir Plast Esthet, 2007.

Lanzetta, M., Petruzzo, P., Dubernard, J. M., Margreiter, R., Schuind, F., Breidenbach, W., Nolli, R., Schneeberger, S., van Holder, C., Gorantla, V. S., Pei, G., Zhao, J., Zhang, X. Second report (1998-2006) of the International Registry of Hand and Composite Tissue Transplantation. Transpl Immunol 18: 1-6, 2007.

Lengele, B. G., Testelin, S., Dakpe, S., Carton, S., Beziat, J. L., Badet, L., Morelon, E., Dubernard, J. M., Devauchelle, B. ["Facial graft": about the first facial allotransplantation of composite tissues.]. Ann Chir Plast Esthet, 2007.

Gander, B., Brown, CS., Vasilic, D., et al. Composite tissue allotransplantation of the hand and face: a new frontier in transplant and reconstructive surgery. Transpl Int, 19: 868-880, 2006.

Barckley Storey, Allen Furr, Joseph C. Banis, Michael Cunningham, Dalibor Vasilic, MD, Osborne Wiggins, Serge Martinez, Christopher C. Reynolds, Rachael R Ashcraft and John H. Barker. Psychosocial Issues in Composite Tissue Allotransplantation In: Transplantation of Composite Tissue Allografts. Charles W. Hewitt, WP Andrew Lee and Chad R. Gordon (Eds) Springer Science + Business Media, LLC. New York, (Chapter) 32, 2007, Pp. 452-59. ISBN: 978-0-387-74681-4.

Banis, JC., Barker, JH., Cunningham, M., Francoi., CG., Furr, A., Grossi, F., Kon, M., Maldonad., C., Martinez, S., Perez-Abadia, G., Vossen, M., Wiggins, OP. Response to Selected Commentaries on the AJOB Target Article "On the Ethics of Facial Transplantation Research" The American Journal of Bioethics, 4: W1-W9, 2004.

Barker, JH., Vossen, M., Banic, JC.  The Technical, Immunological, and Ethical Feasability of Face Transplantation. Editorial.  International Journal of Surgery, 2: 8-12. February 2004.

JC. Banis, JH. Barker, Response to: M. Kelly and PEM. Butler, Patient Selection for Facial Transplantation I: Anatomical and Surgical Considerations. International Journal of Surgery, 2(2): 115-116, 2004.

L.A. Furr, J.H. Barker, Response to: I. Summerton and R. Agha, Sociological Considerations in Face Transplantation. International Journal of Surgery, 2(2): 83, 2004.

MR. Cunningham, JH. Barker, Response to: A. Clarke and P.E.M. Butler Patient Selection for Facial Transplantation II: Psychological Considerations. International Journal of Surgery, 2(2): 117-118, 2004.

MR. Cunningham, JH. Barker, Response to: R. Farrer, Psychological Considerations in Face Transplantation. International Journal of Surgery, 2(2): 78-79, 2004.

OP. Wiggins and JH. Barker, Response to: Rev. Peter Haughton, Ethical Considerations of Facial Transplantation Research. International Journal of Surgery, 2(2): 81-82, 2004.

OP. Wiggins, JH. Barker. Response to: G. Thorburn, S. Hettiaratchy, R. Ashcroft and PEM. Butler, Patient Selection for Facial Transplantation III: Ethical Considerations. International Journal of Surgery, 2(2): 119, 2004.

Wiggins, OP., Barker, JH., Martinez, S., Vossen, M., Maldonado, C., Grossi, F., Francois, CG., Cunningham, M., Perez-Abadia, G., Kon, M., and Banis, JC. On the Ethics of Facial Transplantation Research. American Journal of Bioethics, 4(3): 1-12, 2004.

Barker, JH., Francois, CG., Frank, JM., Maldonado, C.  Composite tissue allotransplantation (CTA): Present state and future outlook. Transplantation, 73(5): 832-35, 2002.

Vossen, M., Molfese, DL., Fonaryova-Key, A., Kelly, S., Maldonado, C., Kon, M., Barker, JH. Brain plasticity following hand transplantation. European Surgical Research. 34(S1): 4, 2002 (ABSTRACT)

Barker, JH.., Breidenbach, W., Hewitt, CW. Proceedings of the 2nd International Symposium on Composite Tissue Allotranplantation: Special Issue (Invited Section Editor) Microsurgery, 20(8): 2000.

Francois C, Breidenbach WC, Maldonado C, Kakoulidis T, Dubernard J, Pei G, Ren X, Barker JH. Hand transplantation: comparisons and observations of the first four clinical cases. Microsurgery, 20(8): 360-371, 2000.

Gorantla ,V., Maldonado, C.. Frank, J., Barker, JH. Composite tissue allotransplantation (CTA): Current Status and Future Insights” European J Trauma, 7(6): 267-274, 2000.

Jones, JW., Gruber, SA., Barker, JH., Breidenbach, WC. Successful hand transplantation: One-year follow-up. New England Journal of Medicine, 343(7): 468-473, 2000.

Barker, JH., Jones, JW., Breidenbach, WC. Composite Tissue Transplantation; A Clinical Reality? Transplantation Proceedings (Invited Editor), 30(6): 2686-2787, 1998.

 

Related Work of Others:

Lineaweaver WC. Face transplants and the era of reconstructive transplantation. Ann Plast Surg. 2009 Mar;62(3):225.

Mathes DW, Kumar N, Ploplys E. A survey of North American burn and plastic surgeons on their current attitudes toward facial transplantation. J Am Coll Surg. 2009 Jun;208(6):1051-8 e3.

Park EE, Genden EM. Facial transplantation: the next frontier in head and neck reconstruction. Facial Plast Surg Clin North Am. 2009 May;17(2):271-7.

Wu, S., Xu, H., Ravindra, K., et al. Composite Tissue Allotransplantation: Past, Present and Future-The History and Expanding Applications of CTA as a New Frontier in Transplantation. Transplant Proc 41: 463-465, 2009.

Chenggang, Y., Yan, H., Xudong, Z., Binglun, L., Hui, Z., Xianjie, M., Li, Y., Xing, F., Yunjing, L., Kaihua, L., Huiyuan, L., Yan, Z., Guoyou, Z., Shuzhong, G. Some issues in facial transplantation. Am J Transplant 8: 2169-2172, 2008.

Dubernard, J. M., Devauchelle, B. Face transplantation. Lancet 372: 603-604, 2008.

Fitchett, J. R. Facial reconstruction - The impact of facial allograft transplantation on surgery. Int J Surg, 2008.

Frey, S. H., Bogdanov, S., Smith, J. C., Watrous, S., Breidenbach, W. C. Chronically Deafferented Sensory Cortex Recovers a Grossly Typical Organization after Allogenic Hand Transplantation. Curr Biol, 2008.

Ravindra, K. V., Wu, S., Bozulic, L., Xu, H., Breidenbach, W. C., Ildstad, S. T. Composite tissue transplantation: a rapidly advancing field. Transplant Proc 40: 1237-1248, 2008.

Wallace, C. G., Wei, F. C. The current status, evolution and future of facial reconstruction. Chang Gung Med J 31: 441-449, 2008.

Burd, A. Face. J Plast Reconstr Aesthet Surg 60: 1173-1174, 2007.

Delaporte, F. [Partial face transplant antropology of surgical breakthrough]. Rev Prat 57: 2314-2317, 2007.

Delaporte, F. [Partial facial transplantation. A surgical breakthrough]. Rev Prat 57: 2314-2317, 2007.

Devauchelle, B. [A lesson in humility]. Rev Stomatol Chir Maxillofac 108: 475-477, 2007.

Kratz, G. [Facial transplantation...playground or medical achievement?]. Lakartidningen 104: 204-205, 2007.

Lengele, B., Testelin, S., Cremades, S., Devauchelle, B. Facing up is an act of dignity: lessons in elegance addressed to the polemicists of the first human face transplant. Plast Reconstr Surg 120: 803-806, 2007.

Megee, D. M., Berry, N., Russell, R. C., et al. Tissue engineering: bridging the gap between replantation and composite tissue allografts. Clin Plast Surg 34: 319-325, 2007.

Morris, P., Bradley, A., Doyal, L., et al. Face Transplantation: A Review of the Technical, Immunological, Psychological and Clinical Issues with Recommendations for Good Practice. Transplantation 83: 109-128, 2007.

Sacks, J. M., Keith, J. D., Fisher, C., Lee, W. P. The Surgeon's Role and Responsibility in Facial Tissue Allograft Transplantation. Ann Plast Surg 58: 595-601, 2007.

Tobin, G. R., Breidenbach, W. C., 3rd, Pidwell, D. J., et al. Transplantation of the hand, face, and composite structures: evolution and current status. Clin Plast Surg 34: 271-278, 2007.

Birchall, MA., Lorenz, RR., Berke, GS., Genden, EM., Haughey, BH., Siemionow, M., et al. (2006). Laryngeal transplantation in 2005: a review. Am J Transplant, 6(1): 20-26.16433752. 

Butler, PE., Hettiaratchy, S., & Clarke, A. (2006). Facial transplantation: A new gold standard in facial reconstruction? J Plast Reconstr Aesthet Surg, 59(3): 211-212.16492405.

Butler, PE., Hettiaratchy, S., Clarke, A. Managing the risks of facial transplantation. Lancet, 368: 561-563, 2006.

Devauchelle, BBL., Lengelé, B., Morelon, E., Testelin, S., Michallet, M., D’Hauthuille, CJMD. First human face allograft: early report. The Lancet, 1-7, 2006.

First allograft face transplantation: report on first three months. Transplantation, 82: 391-392, 2006.

Gordon, CR., Nazzal, J., Lozano-Calderan, SA., et al. From experimental rat hindlimb to clinical face composite tissue allotransplantation: Historical background and current status. Microsurgery, 2006.

Kanitakis, J., Badet, L., Petruzzo, P., et al. Clinicopathologic monitoring of the skin and oral mucosa of the first human face allograft: Report on the first eight months. Transplantation 82: 1610-1615, 2006.

Morris, P., Bradley, A., Doyal, L., et al. Facial Transplantation: Working Party report.  2003  [cited April 30, 2006]; Available from: http://www.rcseng.ac.uk/rcseng/content/publications/docs/facial_transplantation.html

Morris, P., Bradley, A., Doyal, L., et al. Facial Transplantation: Working Party report 2nd Edition, November 2006.[cited December 11, 2006]; Available from: https://neurophilosophy.wordpress.com/files/2006/11/facial_transplantation_final.pdf

Nau, JY. (2006). [Story of the first partial face transplant]. Rev Med Suisse, 2(47): 76.16465953.

O'Dowd, A. Royal College of Surgeons give cautious approval for face transplants. Bmj 333: 1035, 2006.

Pellerin, D. [Partial-facial allograft or allotransplantation of a portion of the face?]. J Chir, (Paris) 143: 75, 2006.

Preminger, BA., Fins, JJ. Face transplantation: an extraordinary case with lessons for ordinary practice. Plast Reconstr Surg, 118: 1073-1074, 2006.

Renshaw, A., Diver, A., Clarke, A., et al. Facial transplantation: A real option in facial reconstruction? International Journal of Surgery, 4: 94-96, 2006.

Rohrich, RJ., Longaker, MT., & Cunningham, B. (2006). On the Ethics of Composite Tissue Allotransplantation (Facial Transplantation). Plast Reconstr Surg, 117(6): 2071-2073.16651986.

Simpson, P., & Batchelor, A. (2006). Face transplants. Lancet, 367(9509): 469.16473114.

The English position: Position paper of the Royal College of Surgeons of England. (2006). South Med J, 99(4): 431.16634267.

The United States position: Position paper of the American Society for Reconstructive Microsurgery on Facial Transplantation. (2006). South Med J, 99(4): 430.16634266.

Toure, G., Meningaud, J. P., Bertrand, J. C., & Herve, C. (2006). Facial transplantation: a comprehensive review of the literature. J Oral Maxillofac Surg, 64(5): 789-793.16631486.

Walton, R. L., & Levin, L. S. (2006). Face transplantation: the view from Duke University and the University Of Chicago. South Med J, 99(4): 417-418.16634261.

Warnke, P. H. Repair of a human face by allotransplantation. Lancet, 368: 181-183, 2006.

Butler, PE., Clarke, A., & Hettiaratchy, S. (2005). Facial transplantation. Bmj, 331(7529: 1349-1350.16339221.

Clark, PA. (2005a). Face transplantation: a medical perspective. Med Sci Monit, 11(1): RA1-6.15614201.

Clarke, A., & Butler, PE. (2005). Facial transplantation: adding to the reconstructive options after severe facial injury and disease. Expert Opin Biol Ther, 5(12): 1539-1546.16318418.

The first facial transplant. (2005). Lancet, 366(9502), 1984.16338435.

Hartman, RG. (2005). Face value: challenges of transplant technology. Am J Law Med, 31(1): 7-46.15895814.

Jiang, HQ., Wang, Y., Hu, X., Li, Y., Li, J.  Composite Tissue Allograft Transplantation of Cephalocervical Skin Flap and Two Ears (Case Report).  Plastic and Reconstructive Surgery. March, 2005.

Position of the American Society for Reconstructive Microsurgery on Facial Transplantation.(2006).Retrieved March 15, 2005, from http://www.microsurg.org/asrmFTP.pdf

Marco Lanzetta, Palmina Petruzzo, Raimund Margreiter, Jean Michel Dubernard, Frederic Schuind, Warren Breidenbach, Stefano Lucchina, Stefan Schneeberger, Carlo van Holder, Darla Granger, Guoxian Pei, Jinmin Zhao, Xinying Zhang.  The International Registry on Hand and Composite Tissue Transplantation.  Transplantation, 79(9): 1210-1214.  2005.

Nau, JY. (2005). [History of the first partial face transplant]. Rev Med Suisse, 1(46): 3002.16429977.

Siemionow, MZ., Demir, Y., Sari, A., & Klimczak, A. (2005). Facial tissue allograft transplantation. Transplant Proc, 37(1): 201-204.15808593.

Siemionow, M., & Agaoglu, G. (2005). Allotransplantation of the face: how close are we? Clin Plast Surg, 32(3): 401-409, vii.15979478.

Siemionow, M., Ozmen, S., & Demir, Y. (2004). Prospects for facial allograft transplantation in humans. Plast Reconstr Surg, 113(5): 1421-1428.15060356.

Spurgeon, B. Surgeons pleased with patient's progress after face transplant. Bmj, 331: 1359, 2005.

Tagliacozzi G.  De curtorum chirurgia per insitionem. Venice, Italy, University of Milan Library, 1597.

Butler, PE., Clarke, A., & Ashcroft, RE. (2004). Face transplantation: when and for whom? Am J Bioeth, 4(3): 16-17; discussion W23-31.16192126.

Clark, J. (2004). Face transplants technically possible, but "very hazardous". Cmaj, 170(3): 323.14757657.

Hettiaratchy, S., Randolph, MA., Petit, F., Lee, WP., & Butler, PE. (2004). Composite tissue allotransplantation--a new era in plastic surgery? Br J Plast Surg, 57(5): 381-391.15191817.

Petit, F., Paraskevas, A., & Lantieri, L. (2004). A surgeons' perspective on the ethics of face transplantation. Am J Bioeth, 4(3): 14-16; discussion W23-31.16192125.

Petit, F., Paraskevas, A., Minns, AB., Lee, WP., & Lantieri, LA. (2004). Face transplantation: where do we stand? Plast Reconstr Surg, 113(5): 1429-1433.15060357.

Levi, DM., Tzakis, AG., Kato, T., Madariaga, J., Mittal, NK., Nery, J., et al. (2003). Transplantation of the abdominal wall. Lancet, 361(9376): 2173-2176.12842369.

Listen to the patients. (2003). New Sci, 180(2423), 3.15015508.

Toledo-Pereyra, L. H. (2003). Classics of modern surgery: the unknown man of Alexis Carrel-father of transplantation. J Invest Surg, 16(5): 243-246.14527882.

Edgerton, M. T. (2002). Early plastic surgery at the Johns Hopkins Hospital. Plast Reconstr Surg, 110(1): 229-233.12087260.

Hettiaratchy, S., & Butler, PE. (2002). Face transplantation--fantasy or the future? Lancet, 360(9326): 5-6.12114034.

Zipfel, S., Schneider, A., Wild, B., Lowe, B., Junger, J., Haass, M., et al. (2002). Effect of depressive symptoms on survival after heart transplantation. Psychosom Med, 64(5): 740-747.12271104.

Calne, RY. (2001). The future of organ transplantation: from the laboratory to the clinic. Philos Trans R Soc Lond B Biol Sci, 356(1409): 767-771.11375079.

Meirer, R., Gurunluoglu, R., & Siemionow, M. (2001). Neurogenic perspective on vascular endothelial growth factor: review of the literature. J Reconstr Microsurg, 17(8): 625-630.11740659.

Herndon, JH., (2000). Composite-tissue transplantation--a new frontier. N Engl J Med, 343(7): 503-505.10944569.

Kann, BR., Furnas, DW., & Hewitt, CW. (2000). Past, present, and future research in the field of composite tissue allotransplantation. Microsurgery, 20(8): 393-399.11150990.

Dubernard J-M, Owen E, Herzberg G, et al. Human hand allograft: report on first 6 months. Lancet 1999; 353: 1315-20.

Lee, WP., & Mathes, DW. (1999). Hand transplantation: pertinent data and future outlook. J Hand Surg [Am], 24(5): 906-913.10509267

Lundborg, G. (1999). Hand transplantation. Scand J Plast Reconstr Surg Hand Surg, 33(4): 369-371.10614743.

Hewitt, CW. (1998). Update and outline of the experimental problems facing clinical composite tissue transplantation. Transplant Proc, 30(6): 2704-2707.9745550.

Zimmermann, K. W. (1998). One  Leg in the Grave: The Miracle of the Transplantation of the Black Leg by the Saints Cosmas and Damian: Elsevier/Bunge, Maarssen.

Black, K., & Hewitt, C. (1991). Composite Tissue Transplantation Workshop. Washington, DC: Department of Veterans Affairs, Rehabilitation Research and Development Service. 

Lechler, R., Gallagher, RB., & Auchincloss, H. (1991). Hard graft? Future challenges in transplantation. Immunol Today, 12(7): 214-216.1679634.

Kahan, BD. (1983). Cosmas and Damian revisited. Transplant Proc, 15(4 Suppl 1-2): 2211-2216.6364505.

Black, KS., Hewitt, CW., Fraser, LA., Osborne, JG., Achauer, BM., Martin, DC., et al. (1982). Cosmas and Damian in the laboratory. N Engl J Med, 306(6): 368-369.7033792 .

Zhong-Wei, C., Meyer, V. E., Kleinert, H. E., & Beasley, R. W. (1981). Present indications and contraindications for replantation as reflected by long-term functional results. Orthop Clin North Am, 12(4): 849-870.7322515.

Gnud, i. M., & al., e. (1976). The sympathetic slave. In: The life and times of Gaspare Tagliacozzi. Los Angeles, CA: Zeitlin and Ver Brugge.

Danilevicius, Z. (1967). SS. Cosmas and Damian. The patron saints of medicine in art. Jama, 201(13): 1021-1025.4861502.

Gnudi, MT., Webster, JP., & Tagliacozzi, G. (1950). The life and times of Gaspare Tagliacozzi : surgeon of Bologna, 1545-1599 ; with a documented study of the scientific and cultural life of Bologna in the sixteenth century. New York: H. Reichner.

Jacobus, & Levasti, A. (1924). Leggenda aurea; volgarizzamento toscano del trecento. Firenze: Libreria editrice Fiorentina.

 

 

Technical-Surgical

(Face and Hand Transplantation)

Our Work: 

Banis, J., & Barker, J. (2004). Patient selection for facial transplantation I: Anatomical and surgical considerations. International Journal of Surgery, 2(2): 115-116.

Ren XP, Shirbacheh MV, Ustuner ET, Zdichavsky M, Edelstein J, Maldonado C, Breidenbach WC, Frank J, Jones J and Barker JH.  Radial forelimb osteomyocutaneous flap as a pre-clinical composite tissue allograft (CTA) model in swine. Microsurgery, 20(3): 143-149, 2000. 

Ustuner ET, Majzoub RK, Ren X, Edelstein J, Zdichavsky M, Maldonado C, Breidenbach WC, Barker JH. Swine composite tissue allotransplant model for pre-clinical hand transplant studies. Microsurgery, 20(8): 400-406, 2000.

Banis, JC, Acland, R., Managing the outer limits of reconstruction with microsurgical free tissue transfer. Arch. of Surg, 1984; 119: 673-679.

 

Related Work of Others:

Washington KM, Solari MG, Sacks JM, Horibe EK, Unadkat JV, Carvell GE, et al. A model for functional recovery and cortical reintegration after hemifacial composite tissue allotransplantation. Plast Reconstr Surg. 2009 Feb;123(2 Suppl):26S-33S.

Barth, R. N., Bluebond-Langner, R., Nam, A., et al. Facial subunit composite tissue allografts in nonhuman primates: I. Technical and immunosuppressive requirements for prolonged graft survival. Plast Reconstr Surg 123: 493-501, 2009.

Brucker, M., Sati, S., Spangenberger, A., Weinzweig, J. Long-term fate of transplanted autologous fat in a novel rabbit facial model. Plast Reconstr Surg 122: 749-754, 2008.

Cordeiro, P. G. Frontiers in free flap reconstruction in the head and neck. J Surg Oncol 97: 669-673, 2008.

Follmar, K. E., Baccarani, A., Das, R. R., Mukundan, S., Levin, L. S., Erdmann, D., Marcus, J. R. Osteocutaneous face transplantation. J Plast Reconstr Aesthet Surg, 2008.

Guntinas-Lichius, O. Outcomes 18 months after the first human partial face transplantation. N Engl J Med 358: 2179-2180; author reply 2180, 2008.

Guo, S., Han, Y., Zhang, X., Lu, B., Yi, C., Zhang, H., Ma, X., Wang, D., Yang, L., Fan, X., Liu, Y., Lu, K., Li, H. Human facial allotransplantation: a 2-year follow-up study. Lancet 372: 631-638, 2008

Landin, L., Cavadas, P. C., Gonzalez, E., Rodriguez, J. C., Caballero, A. Functional outcome after facial allograft transplantation in rats. J Plast Reconstr Aesthet Surg, 2008.

Lantieri, L., Meningaud, J. P., Grimbert, P., Bellivier, F., Lefaucheur, J. P., Ortonne, N., Benjoar, M. D., Lang, P., Wolkenstein, P. Repair of the lower and middle parts of the face by composite tissue allotransplantation in a patient with massive plexiform neurofibroma: a 1-year follow-up study. Lancet 372: 639-645, 2008

Leon, X., Pujol, A., Lopez, M., Garcia, J., Pons, G., Sanudo, J. R., Masia, J., Quer, M. [Larynx Transplant: A Therapeutic Option for the 21st Century? Literature Review.]. Acta Otorrinolaringol Esp 59: 127-138, 2008.

Meningaud, J. P., Paraskevas, A., Ingallina, F., Bouhana, E., Lantieri, L. Face transplant graft procurement: a preclinical and clinical study. Plast Reconstr Surg 122: 1383-1389, 2008.

Silverman, R. P., Banks, N. D., Detolla, L. J., Shipley, S. T., Panda, A., Sanchez, R. A., Azimzadeh, A. M., Pierson, R. N., 3rd, Wang, D., Rodriguez, E. D., Holton, L. H., 3rd, Bartlett, S. T. A Heterotopic Primate Model for Facial Composite Tissue Transplantation. Ann Plast Surg 60: 209-216, 2008.

Baccarani, A., Follmar, K. E., Das, R. R., et al. A pilot study in sub-SMAS face transplantation: defining donor compatibility and assessing outcomes in a cadaver model. Plast Reconstr Surg 119: 121-129, 2007.

Devauchelle, B., Lengele, B. G., Moure, C., Cremades, S., D'Hauthuille, C., Taha, F., Bitar, G., Testelin, S., Dubernard, J. M. [Mediatisation and "facial graft" or "to whom belongs the facial graft"?]. Ann Chir Plast Esthet 52: 528-530, 2007.

Duque, E., Duque, J., Nieves, M., Mejia, G., Lopez, B., Tintinago, L. Management of larynx and trachea donors. Transplant Proc 39: 2076-2078, 2007.

Gonzalez-Garcia, E., Landin-Jarillo, L., Piqueras-Del Rey, A. [Functional recovery in hemifacial transplants in rats.]. Rev Neurol 45: 389-392, 2007.

Landin, L., Cavadas, P. C., Carrera, A., et al. Human face/scalp alloflap harvesting technique. Plast Reconstr Surg 119: 1114-1115, 2007.

McCrary, B. F. Hyperbaric oxygen (HBO2) treatment for a failing facial flap. Postgrad Med J 83: e1, 2007.

Paraskevas A, Ingallina F, Meningaud JP, Lantieri L.Face allotransplantation: anatomical study, potential partial and total facial allografts harvestings and clinical application. Ann Chir Plast Esthet. 2007.

Siemionow, M., Agaoglu, G. Tissue transplantation in plastic surgery. Clin Plast Surg 34: 251-269, 2007.

Ulusal, B. G., Ulusal, A. E., Lin, J. Y., Tan, B. K., Wong, C. H., Song, C., Wei, F. C. Anatomical and technical aspects of harvesting the auricle as a neurovascular facial subunit transplant in humans. Plast Reconstr Surg 120: 1540-1545, 2007.

Wang, H. Y., Li, Q. F., Zheng, S. W., Chen, B., Li, Y. P., Tang, L. J., Chang, T. S. Cadaveric comparison of two facial flap-harvesting techniques for alloplastic facial transplantation. J Plast Reconstr Aesthet Surg 60: 1175-1181, 2007.

Anatomical basis for face transplantation. Transplantation, 82: 862-863, 2006.

Baccarani, A., Follmar, K. E., Baumeister, S. P., et al. Technical and anatomical considerations of face harvest in face transplantation. Ann Plast Surg 57: 483-488, 2006.

Siemionow, M., Agaoglu, G. The issue of "facial appearance and identity transfer" after mock transplantation: a cadaver study in preparation for facial allograft transplantation in humans. J Reconstr Microsurg, 22: 329-334, 2006.

Siemionow, M., Agaoglu, G., & Unal, S. (2006). A cadaver study in preparation for facial allograft transplantation in humans: part II. Mock facial transplantation. Plast Reconstr Surg, 117(3): 876-885; discussion 886-878.16525279.

Siemionow, M., Papay, F., Kulahci, Y., et al. Coronal-posterior approach for face/scalp flap harvesting in preparation for face transplantation. J Reconstr Microsurg, 22: 399-405, 2006.

Siemionow, M., Unal, S., Agaoglu, G., & Sari, A. (2006). A cadaver study in preparation for facial allograft transplantation in humans: part I. What are alternative sources for total facial defect coverage? Plast Reconstr Surg, 117(3): 864-872; discussion 873-865.16525277.

Wang, H. Y., Li, Q. F., Zheng, S. W., et al. [Strategy study of harvesting total facial flap and donor choice for allograft transplantation in cadaver]. Zhonghua Zheng Xing Wai Ke Za Zhi 22: 331-333, 2006.

Yazici, I., Unal, S., Siemionow, M. Composite hemiface/calvaria transplantation model in rats. Plast Reconstr Surg, 118: 1321-1327, 2006.

Zhang, XD., Guo, SZ., Han, Y., et al. [A hemifacial transplantation model in hares]. Zhonghua Zheng Xing Wai Ke Za Zhi, 22: 204-207, 2006.

Zheng, S. W., Li, Q. F., Jiang, H., et al. [Establishment of composite facial and scalp allograft transplantation model in canine]. Zhonghua Zheng Xing Wai Ke Za Zhi, 22: 298-302, 2006.

 Horch, RE., Jeschke, MG., Spilker, G., Herndon, DN., & Kopp, J. (2005). Treatment of second degree facial burns with allografts--preliminary results. Burns, 31(5): 597-602. 15993304.

Unal, S., Agaoglu, G., Zins, J., & Siemionow, M. (2005). New surgical approach in facial transplantation extends survival of allograft recipients. Ann Plast Surg, 55(3): 297-303.16106171.

Demir, Y., Ozmen, S., Klimczak, A., Mukherjee, AL., & Siemionow, M. (2004). Tolerance induction in composite facial allograft transplantation in the rat model. Plast Reconstr Surg, 114(7): 1790-1801.15577350.

Frey, M., Giovanoli, P., Tzou, C. H., et al. Dynamic reconstruction of eye closure by muscle transposition or functional muscle transplantation in facial palsy. Plast Reconstr Surg 114: 865-875, 2004.

Martin Kelly, Peter EM. Butler. Patient Selection for Facial Transplantation I: Anatomical and Surgical Considerations. International Journal of Surgery 2: 2004.

Peter J Morris, JA. Bradley, L. Doyal, M. Earley, P. Hagan, M. Milling, N. Rumsey.  Facial Transplantation: A working party report from the Royal College of Surgeons of England.  Trasnplantation,  77(3): 330-338. February, 2004.

Jiang Hui-qing, Hu Xin-bao, Li You-sheng, Wang Young, Li Yuan-xin, Wang Jun, Hong Zhi-jian, Xie Wei-guang, Chien Yifei, Li Jie-shou.  "Allograft allotransplantation with composite tissue of two ears and skin of head and neck: A report of one case" Chinese Journal of Plastic Surgery,  Nov. 2003, 19(6): 416-419.

Toljanic, JA., Heshmati, RH., Walton, RL. Early rehabilitation of facial defects using interim removable prostheses: report of two clinical cases. Ann Plast Surg, 2003; 50: 188-191.

Ulusal, BG., Ulusal, AE., Ozmen, S., Zins, JE., & Siemionow, MZ. (2003). A new composite facial and scalp transplantation model in rats. Plast Reconstr Surg, 112(5): 1302-1311.14504514.

Wilhelmi, BJ., Kang, RH., Movassaghi, K., Ganchi, PA., Lee, WP. First successful replantation of face and scalp with single-artery repair: model for face and scalp transplantation. Ann Plast Surg, 2003; 50: 535-540.

Eduardo Bermu Dez, L., Santamaria, A., Romero, T., & Caldero, DF. (2002). Experimental model of facial transplant. Plast Reconstr Surg, 110(5), 1374-1375.12360095.

Fageeh, W., Raffa, H., Jabbad, H., & Marzouki, A. (2002). Transplantation of the human uterus. Int J Gynaecol Obstet, 76(3): 245-251.11880127.

Ozer, K., Zielinski, M., Unsal, M., & Siemionow, M. (2002). Development of mouse cremaster transplantation model for intravital microscopic evaluation. Microcirculation, 9(6): 487-495.12483546.

Mackinnon, SE., Doolabh, VB., Novak, CB., & Trulock, EP. (2001). Clinical outcome following nerve allograft transplantation. Plast Reconstr Surg, 107(6): 1419-1429.11335811.

Pribaz, JJ., Fine, NA. Prefabricated and prelaminated flaps for head and neck reconstruction. Clinical Plastic Surgery, 2001; 28: 261-272.

Bain, J. R. (2000). Peripheral nerve and neuromuscular allotransplantation: current status. Microsurgery, 20(8): 384-388.11150988.

Hoekstra, K., Hudson, DA., Smith, AW. The use of pedicled expanded flaps for aesthetic resurfacing of the burned face. Ann Plastic Surgery, 2000; 45: 1-6.

Dubernard, JM., Owen, E., Herzberg, G., Martin, X., Guigal, V., Dawahra, M., et al. (1999). [The first transplantation of a hand in humans. Early results]. Chirurgie, 124(4): 358-365; discussion 365-357.10546388.

Jean-Michel Dubenard, Earl Owen, Guillaume Herzberg, Marco Lanzetta, Xavier Martin, Hari Kapila, Marwan Dawahra, Nadey S. Hakim.  Human hand allograft: report on first 6 months.   The Lancet, 353: 1315-1320, April 1999.

Latifoglu, O., Ayhan, S., & Atabay, K. (1999). Total face reconstruction: skin graft versus free flap. Plast Reconstr Surg, 103(3): 1076-1078.10077107.

Jones, TR., Humphrey, PA., & Brennan, DC. (1998). Transplantation of vascularized allogeneic skeletal muscle for scalp reconstruction in renal transplant patient. Transplant Proc, 30(6): 2746-2753.9745560.

Thomas, A., Obed, V., Murarka, A., and Malhotra, G., Total face and scalp replantation; Case report, Plastic Reconstructive Surgery. 1998; 102: 2085-87.

Angrigiani, C., Grilli, D. Total face reconstruction with one free flap. Plast Reconstr Sur, 1997; 99: 1566-75.

Cheng, K., Zhou, S., Jiang, K., Wang, S., Dong, J., Huang, W., and Chang, T. Microsurgical replantation of the avulsed scalp: report of 20 cases Plastic Reconstructive Surgery, 1996; 97: 1099-1108.

Mackinnon, SE. (1996). Nerve allotransplantation following severe tibial nerve injury. Case report. J Neurosurg, 84(4), 671-676.8613862.

Arashiro, K., Ohtsuka, H., Ohtani, K., Yamamoto, M., Nakaoka, H., Watanabe, T., et al. (1995). Entire scalp replantation: case report and review of the literature. J Reconstr Microsurg, 11(4): 245-250.7562715.

Lee, WP., Pan, YC., Kesmarky, S., Randolph, MA., Fiala, TS., Amarante, MT., et al. (1995). Experimental orthotopic transplantation of vascularized skeletal allografts: functional assessment and long-term survival. Plast Reconstr Surg, 95(2): 336-349; discussion 350-333.7824614.

Beumer, J. III, Roumanas, E., Nishimura, R. Advances in osseointegrated implants for dental and facial rehabilitation following major head and neck surgery. Semin Surg Oncol, 1995; 11: 200-207.

Langer, R., & Vacanti, JP. (1993). Tissue engineering. Science, 260(5110): 920-926.8493529.

Hovius, SE., Stevens, HP., van Nierop, PW., Rating, W., van Strik, R., & van der Meulen, JC. (1992). Allogeneic transplantation of the radial side of the hand in the rhesus monkey: I. Technical aspects. Plast Reconstr Surg, 89(4): 700-709.1546083.

Hovius, SE., Stevens, HP., Van Nierop, PW., Godschalk, M., Kusuma, A., Deelen, G., et al. (1992). Replantation of the radial side of the hand in the rhesus monkey: anatomical and functional aspects. A preliminary study to composite tissue allografting. J Hand Surg [Br], 17(6): 651-656.1484247.

Mackinnon, SE., & Hudson, AR. (1992). Clinical application of peripheral nerve transplantation. Plast Reconstr Surg, 90(4): 695-699.1410009.

Bain, J. R., Mackinnon, S. E., Hudson, A. R., Falk, R. E., Falk, J. A., Hunter, D. A., et al. (1989). Preliminary report of peripheral nerve allografting in primates immunosuppressed with cyclosporin A. Transplant Proc, 21(1 Pt 3): 3176-3177.2705277.

Yaffe, B., & Shvoron, A. (1986). Successful replantation of a totally avulsed scalp. J Reconstr Microsurg, 2(3): 171-173.3712323.

Egerszegi, EP., Samulack, DD., & Daniel, RK. (1984). Experimental models in primates for reconstructive surgery utilizing tissue transplants. Ann Plast Surg, 13(5): 423-430.6393844.

Carrel, A. (1983). Landmark article, Nov 14, 1908: Results of the transplantation of blood vessels, organs and limbs. By Alexis Carrel. Jama, 250(7): 944-953.6345837.

Anon. (1964). Hand transplanted from cadaver is reamputated. Med Trib Med News, 5, 23.

Gilbert, R. (1964). Transplant is successful with a cadaver forearm. Med Trib Med News, 5, 20.

 Malt, RA., & McKhann, C. (1964). Replantation of Several Arms. Jama, 189: 716-722.14175645.

 

Immunological

(Face and Hand Transplantation)

Our Work: 

Whitaker, I. S., Duggan, E. M., Alloway, R. R., Brown, C., McGuire, S., Woodle, E. S., Hsiao, E. C., Maldonado, C., Banis, J. C., Jr., Barker, J. H. Composite tissue allotransplantation: a review of relevant immunological issues for plastic surgeons. J Plast Reconstr Aesthet Surg, 2008.

Vasilic, D., Alloway, R. R., Barker, J. H., Furr, A., Ashcroft, R., Banis, J. C., Jr., Kon, M., Woodle, E. S. Risk assessment of immunosuppressive therapy in facial transplantation. Plast Reconstr Surg 120: 657-668, 2007.

Bradford L. Cottrell, M.S., Gustavo Perez-Abadia, M.D., Stephen M. Onifer, Ph.D., David S. Magnuson, Ph.D., Darlene A. Burke, M.A., Federico V. Grossi, M.D., Cedric G. Francois, M.D., John H. Barker M.D., Ph.D., Claudio Maldonado, Ph.D. Neuroregeneration in Composite Tissue Allografts: Effect of Low-Dose FK506 and Mycophenolate Mofetil Immunotherapy, Plast Reconstr Surg 118(3): 615-23, 2006.

Cedric G. Francois, Pascal C.R. Brouha, Luis A. Laurentin-Perez, Gustavo Perez-Abadia, Feerico V. Grossi, John H. Barker, Charles W. Hewitt, Diane J. Pidwell, Moshe Kon, Rajendra Ramsamooj, Claudio Maldonado. Vascularized lymph node transplantation induces graft-versus-host-disease in chimeric hosts. Transplantation. 81(10): 1435-1441, May 27, 2006.

Cottrell, B. L., Perez-Abadia, G., Onifer, S. M., et al. Neuroregeneration in composite tissue allografts: effect of low-dose FK506 and mycophenolate mofetil immunotherapy. Plast Reconstr Surg, 118: 615-623; discussion 624-615, 2006.

Francois, C. G., Brouha, P. C., Laurentin-Perez, L. A., Perez-Abadia, G., Grossi, F. V., Barker, J. H., Hewitt, C. W., Kon, M., Ramsamooj, R., Maldonado, C. Vascularized lymph node transplantation induces graft-versus-host disease in chimeric hosts. Transplantation 81: 1435-1441, 2006

Pascal Brouha, Deepak Naidu, Michael Cunningham, Allen Furr, Ramsey Majzoub, Federico V. Grossi, Cedric G. Francois, Claudio Maldonado, Joseph C. Banis, Serge Martinez, Gustavo Perez-Abadia, Osborne Wiggins, Moshe Kon, John H. Barker Risk Acceptance in Composite Tissue Allotransplantation reconstructive procedures. Microsurgery, 26: 3 144-49. 2006.

Vossen, M., Edelstein, J., Majzoub, R., Zdichavsky, M., Maldonado, C., Perez-Abadia, GA., Voor, M., Orbun, H., Tecimer, T., Francois, C., Kon, M., Barker JH.:  Bone quality and healing in a swine vascularized bone allotransplantation model using cyclosporine-base immunosuppression therapy.  Plast. Reconstr Surg, 115(20): 529-538, 2005.

Vossen, M., Edelstein, J., Majzoub, RK., Maldonado, C., Perez-Abadia, G., Voor, MJ., et al. (2005). Bone quality and healing in a swine vascularized bone allotransplantation model using cyclosporine-based immunosuppression therapy. Plast Reconstr Surg, 115(2): 529-538.15692359.

Vossen, M., Majzoub, RK., Edelstein, J., Perez-Abadia, G., Voor, M., Maldonado, C., et al. (2005). Bone quality in swine composite tissue allografts: effects of combination immunotherapy. Transplantation, 80(4): 487-493.16123723.

Brouha, PCR. , Perez-Abadia, G., Francois, CG., Laurentin-Perez, LA., Gorantla, V., Vossen, M., Tai, C., Pidwell, DJ., Anderson, G., Stadelmann, WK., Hewitt, C., Kon, M., Barker, JH., Maldonado, C. Lymphadenctomy prior to rat hind limb allotransplantation prevents graft-versus-host disease in chimeric hosts. Transplatation International, 17: 41-350, 2004.

Gorantla, V. S., Prabhune, K. A., Perez-Abadia, G., Ildstad, S. T., Maldonado, C., Orhun, H. I., et al. (2003). Composite tissue allotransplantation in chimeric hosts: part I. Prevention of graft-versus-host disease. Transplantation, 75(7): 922-932.12698075.

Perez-Abadia, G., Laurentin-Perez, L., Gorantla, V. S., Francois, C. G., Vossen, M., Brouha, P. C., et al. (2003). Low-dose immunosuppression in a rat hind-limb transplantation model. Transpl Int, 16(12): 835-842.12904844.

Prabhune, KA., Gorantla, VS., Perez-Abadia, G., Francois, CG., Vossen, M., Laurentin-Perez, L. A., et al. (2003). Composite tissue allotransplantation in chimeric hosts part II. A clinically relevant protocol to induce tolerance in a rat model. Transplantation, 76(11): 1548-1555.14702522.

Edelstein, J., Jones, J. W., Ren, X., Ustuner, T., Zdichavsky, M., Perez-Abadia, G., et al. (2002).Donor/recipient skin and whole-blood cyclosporin A levels in a swine composite tissue allograft model: correlation and relationship to rejection. Transplant Proc, 34(4): 1315-1319.12072349.

Fernandez-Botran, R., Gorantla, V., Sun, X., Ren, X., Perez-Abadia, G., Maldonado, C., Ray, M., Barker, JH. Targeting of glycosaminoglycan-cytokine interactions as a novel therapeutic approach in allotransplantation Transplantation, 74(5): 623-9, 2002.

J. Edelstein, J.W. Jones, X. Ren, T. Ustuner, M. Zdichavsky, G. Perez-Abadia, D.K. Granger, A.W. Jevans, C. Maldonado, W. Breidenbach, J.H. Barker and S.A. Gruber.  Donor/Recipient skin and whole-blood cyclosporine A levels in a swine composite tissue allograft model: Correlation and relationship to rejection. Transplantation Proceedings, 34: 1315-19, 2002.

Gorantla VS, Perez-Abadia G, Ren X, Majzoub R, Prabhune KA, Francois CG, Vossen M, Brouha PC, Maldonado C, Pidwell DJ, Breidenbach WC, Granger DK, Barker JH. A clinically feasible protocol to induce tolerance to limb allografts using mixed allogeneic chimerism. (ABSTRACT) Abstract #781, Am J Transplant 1(1): 321, 2001.

Gorantla VS, Barker JH, Jones, JW, Prabhune KA, Maldonado C, Granger DK. Immunosuppressive agents used in transplantation: mechanisms of action, adverse effects and current anti-rejection strategies. Microsurgery, 20(8): 420-429, 2000.

Gorantla, V, Perez-Abadia G, Prabhune K, Orhun H., Kakoulidis T, Majzoub R, Maldonado C, Anderson GL, Ogden L, Breidenbach WC, Ildstad S, Barker JH. Composite tissue allograft (CTA): tolerance induction without graft vs host disease (GvHD). Surgical Forum, 51:578-79, 2000.

Gruber SA, Shirbacheh MV, Jones JW, Barker JH, Breidenbach W. Local drug delivery to composite tissue allografts. Microsurgery, 20(8): 407-411, 2000.

Orhun, H, Perez-Abadia G, Gorantla V,  Voor M, Tseng M, Maldonado C, Andersol GL, Ogden L, Breidenbach WC, Barker JH. Elastic Properties of Bone in Composite Tissue Allotransplantation: the rat hind limb model. Surg Forum, 51:463-65, 2000.

Prabhune, KA., Gorantla, VS., Maldonado, C., Barker, JH., Ildstad, ST. Mixed allogeneic chimerism and tolerance to composite tissue allografts.  Microsurgery, 20(8): 441-447, 2000.

Edelstein J, Tecimer T, Ustuner T, Zdichavsky M, Shirbacheh M, Maldonado C, Breidenbach WC, Ray MB, Jones JW, Barker JH. The effect of tacrolimus based combination therapy on muscle and bone rejection in a pre-clinical composite tissue allograft model.  Transplantation, 67(7): 212, 1999. (ABSTRACT) .

Jones JW, Ustuner T, Zdichavsky M, Edelstein J, Ren S, Maldonado C, Ray M, Jevans AW, Breidenbach WC, Gruber SA, Barker JH. Long-term survival of an extremity composite tissue allograft with FK506-mycophenolate mofetil therapy. Surgery, 126(3): 384-388, 1999. 

Shirbacheh, MV., Harralson, TA., Jones, JW., Breidenbach, WC., Jevans, AW., Maldonado, C., et al. (1999). Pharmacokinetic advantage of intra-arterial cyclosporin A delivery to vascularly isolated rabbit forelimb. II. Dose dependence. J Pharmacol Exp Ther, 289(3): 1191-1195.10336505.

Shirbacheh, MV., Jones, JW., Harralson, TA., Edelstein, J., Tecimer, T., Breidenbach, WC., et al. (1999). Pharmacokinetics of intra-arterial delivery of tacrolimus to vascularly isolated rabbit forelimb. J Pharmacol Exp Ther, 289(3): 1196-1201.10336506.

Shirbacheh, MV., Ren, X., Jones, JW., Breidenbach, WC., Jevans, AW., Fernandez-Botran, G. R., et al. (1999). Pharmacokinetic advantage of intra-arterial cyclosporin A delivery to vascularly isolated rabbit forelimb. I. Model development. J Pharmacol Exp Ther, 289(3): 1185-1190.10336504.

Tecimer, T., Edelstein, J., Shirbacheh, M., Ustuner, T., Zdichavsky, M., Maldonado, C., Breidenbach, WC., Ray, MB., Jones, JW., Barker, JH. The effect of cyclosporine A based combination therapy on bone, muscle and tendon rejection in a composite tissue allograft (CTA) model.  Transplantation, 67(7): 211, 1999. (ABSTRACT). 

Zdichavsky, M., Jones, J., Ustuner, TE., Ren, XJ., Maldonado, C., Breidenbach, W., Gruber, SA., Ray, M. and Barker, JH. Scoring of skin rejection in a swine composite tissue allograft model. J Surgical Research,  85: 1-8, 1999.

Zdichavsky, M., Ustuner, T., Jones, JW., Edelstein, J., Breidenbach, W., Jevans, A., Maldonado, C., Barker, JH. Cyclosporin A combination therapy prolongs composite tissue allograft survival in a swine model. Euro J Surg. Res, 31(Suppl. 1): 34-35 (No. 58) 1999. (ABSTRACT). 

Shirbacheh, MV., Jones, JW., Breidenbach, WC., McCabe, SJ., Barker, JH., Gruber, SA.  The case for local immunosuppression in composite tissue allotransplantation. Transplantation Proceedings, 30(6): 2739-42, 1998. 

Ustuner, ET., Zdichavsky, M., Ren, X., Edelstein, J., Maldonado, C., Ray, M., et al. (1998). Long-term composite tissue allograft survival in a porcine model with cyclosporine/mycophenolate mofetil therapy. Transplantation, 66(12): 1581-1587.9884243.

 

Related Work of Others:

Aisa, Y., Mori, T., Tanikawa, A., Takae, Y., Kato, J., Ikeda, Y., Okamoto, S. Demodicidosis as a cause of facial eruption developing early after allogeneic hematopoietic stem cell transplantation. Transpl Int, 2008.

Kanitakis, J. The challenge of dermatopathological diagnosis of composite tissue allograft rejection: a review. J Cutan Pathol, 2008.

Kuo, Y. R., Shih, H. S., Lin, C. C., Huang, C. C., Yang, J. C., Wu, W. S., Goto, S., Chen, C. L., Lee, W. P. Swine Hemi-Facial Composite Tissue Allotransplantation: A Model to Study Immune Rejection. J Surg Res, 2008.

Madani, H., Hettiaratchy, S., Clarke, A., Butler, P. E. Immunosuppression in an emerging field of plastic reconstructive surgery: composite tissue allotransplantation. J Plast Reconstr Aesthet Surg 61: 245-249, 2008.

Nasir, S., Bozkurt, M., Klimczak, A., Siemionow, M. Large antigenic skin load in total abdominal wall transplants permits chimerism induction. Ann Plast Surg 61: 572-579, 2008.

Pomahac, B., Aflaki, P., Chandraker, A., Pribaz, J. J. Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery. Transplantation 85: 1693-1697, 2008.

Swearingen, B., Ravindra, K., Xu, H., Wu, S., Breidenbach, W. C., Ildstad, S. T. Science of composite tissue allotransplantation. Transplantation 86: 627-635, 2008.

Vincenti, F., Kirk, A. D. What's next in the pipeline. Am J Transplant 8: 1972-1981, 2008.

Clavijo-Alvarez, J. A., Hamad, G. G., Taieb, A., et al. Pharmacologic approaches to composite tissue allograft. J Hand Surg [Am] 32: 104-118, 2007.

Duhamel, P., Bey, E., Petit, F., Cariou, J. L. [Experimental and clinical experience of composite tissues allotransplantation in reconstructive surgery]. Ann Chir Plast Esthet 52: 399-413, 2007.

Horner, B. M., Randolph, M. A., Huang, C. A., Butler, P. E. Skin tolerance: in search of the Holy Grail. Transpl Int, 2007.

Petit, F. [The future of immunotherapy for composite tissues allotransplantation]. Ann Chir Plast Esthet 52: 502-508, 2007.

Pidwell, D. J., Burns, C. The immunology of composite tissue transplantation. Clin Plast Surg 34: 303-317, 2007.

Sacks, J. M., Horibe, E. K., Lee, W. P. Cellular therapies for prolongation of composite tissue allograft transplantation. Clin Plast Surg 34: 291-301, 2007.

Hettiaratchy, S., & Butler, PE. (2006). Tolerance induction in composite facial allograft transplantation in the rat model. Plast Reconstr Surg, 117(3): 1043-1044; author reply 1044-1045.16525312.

Petit, F., Lantieri, L., Randolph, MA., & Lee, WP. (2006). [Future research in immunology for composite tissue allotransplantation]. Ann Chir Plast Esthet, 51(1): 11-17.16356619.

Kanitakis, J., Petruzzo, P., Jullien, D., Badet, L., Dezza, M. C., Claudy, A., et al. (2005). Pathological score for the evaluation of allograft rejection in human hand (composite tissue) allotransplantation. Eur J Dermatol, 15(4): 235-238.16048749.

Siemionow, M., Demir, Y., Mukherjee, A., & Klimczak, A. (2005). Development and maintenance of donor-specific chimerism in semi-allogenic and fully major histocompatibility complex mismatched facial allograft transplants. Transplantation, 79(5): 558-567.15753845.

Miyagi, M., Ishikawa, Y., Mizuiri, S., Aikawa, A., Ohara, T., & Hasegawa, A. (2005). Significance of subclinical rejection in early renal allograft biopsies for chronic allograft dysfunction. Clin Transplant, 19(4): 456-465.16008588.

Siemionow, MZ., Klimczak, A., & Unal, S. (2005). Different routes of donor-derived hematopoietic stem cell transplantation for donor-specific chimerism induction across MHC barrier. Transplant Proc, 37(1): 62-64.15808547.

Siemionow, M., Ozer, K., Izycki, D., Unsal, M., & Klimczak, A. (2005). A new method of bone marrow transplantation leads to extension of skin allograft survival. Transplant Proc, 37(5): 2309-2314.15964406.

Hettiaratchy, S., Melendy, E., Randolph, MA., Coburn, RC., Neville, DM., Jr., Sachs, DH., et al. (2004). Tolerance to composite tissue allografts across a major histocompatibility barrier in miniature swine. Transplantation, 77(4): 514-521.15084927.

Lanzetta, M., Ayrout, C., Gal, A., Dereli, Z., Wright, B., Lauer, C., et al. (2004). Experimental limb transplantation, part II: excellent return of function and indefinite survival after withdrawal of immunosuppression. Transplant Proc, 36(3): 675-679.15110628.

Ozer, K., Izycki, D., Zielinski, M., & Siemionow, M. (2004). Development of donor-specific chimerism and tolerance in composite tissue allografts under alphabeta-T-cell receptor monoclonal antibody and cyclosporine a treatment protocols. Microsurgery, 24(3): 248-254.15160385

Petit, F., Minns, AB., Nazzal, JA., Hettiaratchy, SP., Lantieri, LA., Randolph, MA., et al. (2004)Prolongation of skin allograft survival after neonatal injection of donor bone marrow and epidermal cells. Plast Reconstr Surg, 113(1): 270-276.14707646.

Wendt, JR., Ulich, T.. and Rao, PN. Long-Term Survival of Human Skin Allografts in Patients with Immunosuppression Plastic Reconstructive Surgery,  2004; 113(5): 1347-54.

Hoodin, F., & Kalbfleisch, KR. (2003). Factor analysis and validity of the Transplant Evaluation Rating Scale in a large bone marrow transplant sample. J Psychosom Res, 54(5): 465-473.12726904.

Kanitakis J, Jullien D, Petruzzo P, Hakim N, Claudy A, Revilard JP et al. Clinicopathologic features of graft rejection of the first human hand allograft. Transplantation,  2003; 76: 688-693

Nankivell, BJ., Borrows, RJ., Fung, CL., O'Connell, PJ., Allen, RD., & Chapman, JR. (2003). The natural history of chronic allograft nephropathy. N Engl J Med, 349(24): 2326-2333.14668458.

Shishido, S., Asanuma, H., Nakai, H., Mori, Y., Satoh, H., Kamimaki, I., et al. (2003). The impact of repeated subclinical acute rejection on the progression of chronic allograft nephropathy. J Am Soc Nephrol, 14(4): 1046-1052.12660340.

Siemionow, M., Gozel-Ulusal, B., Engin Ulusal, A., Ozmen, S., Izycki, D., & Zins, J. E. (2003). Functional tolerance following face transplantation in the rat. Transplantation, 75(9): 1607-1609.12792528.

Siemionow, MZ., Izycki, DM., & Zielinski, M. (2003). Donor-specific tolerance in fully major histocompatibility major histocompatibility complex-mismatched limb allograft trnsplants under an anti-alphabeta T-cell receptor monoclonal antibody and cyclosporine A protocol. Transplantation, 76(12): 1662-1668.14688512.

Pascual, M., Theruvath, T., Kawai, T., Tolkoff-Rubin, N., & Cosimi, A. B. (2002). Strategies to improve long-term outcomes after renal transplantation. N Engl J Med, 346(8): 580-590.11856798.

Siemionow, M., Oke, R., Ozer, K., Izycki, D., & Prajapati, R. (2002). Induction of donor-specific tolerance in rat hind-limb allografts under antilymphocyte serum and cyclosporine A protocol. J Hand Surg [Am], 27(6): 1095-1103.12457363.

Siemionow, M., Ortak, T., Izycki, D., Oke, R., Cunningham, B., Prajapati, R., et al. (2002). Induction of tolerance in composite-tissue allografts. Transplantation, 74(9): 1211-1217.12451256.

Kanitakis, J., Jullien, D., Petruzzo, P., Frances, C., Claudy, A., Revillard, J., et al. (2001). Immunohistologic studies of the skin of human hand allografts: our experience with two patients. Transplant Proc, 33(1-2): 1722.11267485.. 

Strome, M., Stein, J., Esclamado, R., Hicks, D., Lorenz, RR., Braun, W., et al. (2001). Laryngeal transplantation and 40-month follow-up. N Engl J Med, 344(22): 1676-1679.11386266.

Hofmann, GO., & Kirschner, MH. (2000). Clinical experience in allogeneic vascularized bone and joint allografting. Microsurgery, 20(8): 375-383.11150987.

Strome, M. (2000). Human laryngeal transplantation: considerations and implications. Microsurgery, 20(8): 372-374.11150986.

Hricik, DE. (1998). Withdrawal of immunosuppressant: implications for composite tissue allograft transplantation. Transplant Proc, 30(6): 2721-2723.9745554.

Daoud, AJ., et al. A comparison of the safety and efficacy of mycophenolate mofetil, prednisone and    cyclosporine and mycophenolate mofetil, and prednisone and tacrolimus. Transplantation Proceedings 1998; 30: 4079-81.

Stratta, RJ., et al. for the FK/MMF Multi-Center Study Group. Simultaneous use of tacrolimus and mycophenolate mofetil in combined pancreas-kidney transplant recipients: a multi-center report. Transplantation Proceedings 1997; 29: 654-55.

Lubbe, AS., Bergemann, C., Huhnt, W., Fricke, T., Riess, H., Brock, JW., et al. (1996). Preclinical experiences with magnetic drug targeting: tolerance and efficacy. Cancer Res, 56(20): 4694-4701.8840986.

Lubbe, AS., Bergemann, C., Riess, H., Schriever, F., Reichardt, P., Possinger, K., et al. (1996) Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors. Cancer Res, 56(20): 4686-4693.8840985.

Borel, JF., Feurer, C., Gubler, HU., & Stahelin, H. (1994). Biological effects of cyclosporin A: a new antilymphocytic agent. 1976. Agents Actions, 43(3-4): 179-186.7725970.

van den Helder, TB., Benhaim, P., Anthony, JP., McCalmont, TH., & Mathes, SJ. (1994. Efficacy of RS-61443 in reversing acute rejection in a rat model of hind limb allotransplantation. Transplantation, 57(3): 427-433.8108880.

Benhaim, P., Anthony, JP., Lin, LY., McCalmont, TH., & Mathes, SJ. (1993). A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443. Transplantation, 56(4): 911-917.8212216.

Guimberteau, JC., Baudet, J., Panconi, B., Boileau, R., & Potaux, L. (1992). Human allotransplant of a digital flexion system vascularized on the ulnar pedicle: a preliminary report and 1-year follow-up of two cases. Plast Reconstr Surg, 89(6): 1135-1147.1584877.

Gold, ME., Randzio, J., Kniha, H, et al.  Transplantation of vascularized composite mandibular allografts in young cynomolgus monkeys.  Ann Plast Surg , 1991; 26: 125-132.

Lee, WP., Yaremchuk, MJ., Pan, YC., Randolph, MA., Tan, CM., & Weiland, AJ. (1991). Relative antigenicity of components of a vascularized limb allograft. Plast Reconstr Surg, 87(3): 401-411.1998012.

Randzio, J., Kniha, H., Gold, ME., et al.  Growth of vascularized composite mandibular allografts in young rabbits.  Ann Plast Surg, 1991; 26: 140-148. 

Kniha, H., Randzio, J., Gold, ME., Fudem, GM., Cruz, HG., Park, HH., et al. (1989). Growth of forelimb allografts in young rabbits immunosuppressed with cyclosporine. Ann Plast Surg, 22(2): 135-141.2735708.

Yu, LT., England, J., Hickey, WF., Sumner, A., Rhee, E., Rostami, A., et al. (1989). Survival and function of peripheral nerve allografts after cessation of long-term cyclosporine immunosuppression in rats. Transplant Proc, 21(1 Pt 3): 3178-3180.2784925.

Stark, GB., Swartz, W. M., Narayanan, K., & Moller, A. R. (1987). Hand transplantation in baboons. Transplant Proc, 19(5): 3968-3971.3672613.

Daniel, RK., Egerszegi, EP., Samulack, DD., Skanes, SE., Dykes, RW., & Rennie, WR. (1986). Tissue transplants in primates for upper extremity reconstruction: a preliminary report. J Hand Surg [Am], 11(1): 1-8.3944423.

Gratwohl, A., Riederer, I., Graf, E., & Speck, B. (1986). Cyclosporine toxicity in rabbits. Lab Anim, 20(3): 213-220.3795858.

Press, B., Sibley, R., & Shons, A. (1986). Limb allotransplantation in the rat: extended survival and return of nerve function with continuous cyclosporine/prednisone immunosuppression. Ann Plast Surg 16: 313–321.

Hewitt, C. W., Black, K. S., Fraser, L. A., Howard, E. B., Martin, D. C., Achauer, B. M., et al. (1985). Composite tissue (limb) allografts in rats. I. Dose-dependent increase in survival with cyclosporine. Transplantation, 39(4): 360-364.3872490.

Black, KS., Hewitt, CW., Fraser, LA., Howard, EB., Martin, DC., Achauer, BM., et al. (1985). Composite tissue (limb) allografts in rats. II. Indefinite survival using low-dose cyclosporine. Transplantation, 39(4): 365-368.3872491.

Fritz, WD., Swartz, WM., Rose, S., Futrell, JW., & Klein, E. (1984). Limb allografts in rats immunosuppressed with cyclosporin A. Ann Surg, 199(2): 211-215.6607714.

Murray, JE., Merrill, JP., Harrison, JH., Wilson, RE., & Dammin, GJ. (1984). Prolonged survival of human-kidney homografts by immunosuppressive drug therapy. Ann Plast Surg, 12(1): 70-83.6367603.

Siliski, JM., Simpkin, S., & Green, CJ. (1984). Vascularized whole knee joint allografts in rabbits immunosuppressed with cyclosporine A. Arch Orthop Trauma Surg, 103(1): 26-35.6466061.

Starzl, TE. (1984). Landmark perspective: The landmark identical twin case. Jama, 251(19): 2572-2573.6371267.

Furnas, D., Black, K., Hewitt, C., Fraser, L., & Achauer, B. (1983). Cyclosporine and long-term survival of composite tissue allografts (limb transplants) in rats (with historical notes on the role of plastic surgeons in allotransplantation). Transplant Proc, 15: 3063–3068.

Morris, PJ. (1981). Cyclosporin A. Transplantation, 32(5): 349-354.6460358.

Goldberg, VM., Porter, BB., & Lance, EM. (1980). Transplantation of the canine knee joint on a vascular pedicle. A preliminary study. J Bone Joint Surg Am, 62(3), 414-424.7364812

Calne, RY., Rolles, K., White, DJ., Thiru, S., Evans, DB., McMaster, P., et al. (1979). Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers. Lancet, 2(8151): 1033-1036.91781.

Doi, K. (1979). Homotransplantation of limbs in rats. A preliminary report on an experimental study with nonspecific immunosuppressive drugs. Plast Reconstr Surg, 64(5): 613-621.504483.

Lance, EM., Inglis, AE., Figarola, F., & Veith, FJ. (1971). Transplantation of the canine hind limb. Surgical technique and methods of immunosuppression for allotransplantation. A preliminary report. J Bone Joint Surg Am, 53(6): 1137-1149.4937289.

Goldwyn, RM., Beach, PM., Feldman, D., & Wilson, R. E. (1966). Canine limb homotransplantation. Plast Reconstr Surg, 37(3): 184-195.5932982.

Merrill, JP., Murray, JE., Harrison, JH., & Guild, WR. (1984). Landmark article Jan 28, 1956: Successful homotransplantation of the human kidney between identical twins. By John P. Merrill, Joseph E. Murray, J. Hartwell Harrison, and Warren R. Guild. Jama, 251(19): 2566-2571.6371266.

Murray, J., Lang, S., Miller, B., & al., e. (1956). Prolonged functional survival of renal autografts in the dog. Surg Gynecol Obstet, 103: 15.

Murray, J., Merrill, J., & Harrison, J. (1955). Renal homotransplantation in identical twins. Surg Forum, 6, 432.

Guthrie, C. (1912). ApplicationsApplications of blood vessels surgery. In: Blood vessel surgery of blood vessels surgery .New York: Longman Green.

Bunger, C. (1823). Gelungener versuch einer nasenbildung aus einem vollig getrennten hautstuck aus dem beine. J Chir Augenheilk, 4, 569.

         

 

Psychosocial and Ethical

(Facial Transplantation)

Our Work:

Barker, J. H., Brown, C. S., Cunningham, M., Wiggins, O., Furr, A., Maldonado, C., Banis, J. C., Jr. Ethical considerations in human facial tissue allotransplantation. Ann Plast Surg 60: 103-109, 2008.

Barker, J. H., Furr, L. A., McGuire, S., Cunningham, M., Wiggins, O., Storey, B., Maldonado, C., Banis, J. C., Jr. Patient expectations in facial transplantation. Ann Plast Surg 61: 68-72, 2008.

Brown, C. S., Gander, B., Cunningham, M., Furr, A., Vasilic, D., Wiggins, O., Banis, J. C., Vossen, M., Maldonado, C., Perez-Abadia, G., Barker, J. H. Ethical considerations in face transplantation. Int J Surg 5: 353-364, 2007.

John H. Barker, M.D., Ph.D., Allen Furr , Ph.D., Sean McGuire , M.D., Michael Cunningham, Ph.D., Osborne Wiggins, Ph.D., Joseph C Banis , M.D. Response to editorial entitled "On the Ethics of Composite Tissue Allotransplantation (Facial Transplantation) Letter to the Editor Plast Reconstr Surg 119(5):1621-1622, 2007.

Diver, A. J. Investigation of risk acceptance in facial transplantation. Plast Reconstr Surg 119: 2317; author reply 2317, 2007

Furr, L. A., Wiggins, O., Cunningham, M., Vasilic, D., Brown, C. S., Banis, J. C., Jr., Maldonado, C., Perez-Abadia, G., Barker, J. H. Psychosocial implications of disfigurement and the future of human face transplantation. Plast Reconstr Surg 120: 559-565, 2007.

Christopher C. Reynolds; Serge A. Martinez, MD, JD; Allen Furr, PhD; Michael Cunningham, PhD; Jeffrey M. Bumpous, MD; Eric J. Lentsch, MD;  Joseph C. Banis, MD; Dalibor Vasilic, MD; Barckley Storey; Osborne Wiggins, PhD;  Claudio Maldonado, PhD;  Gustavo Perez-Abadia, MD; John H. Barker, MD, PhD. Risk Acceptance in Laryngeal Transplantation. Laryngoscope, 116: 1770–1775, 2006

Ramsey K. Majzoub, Michael Cunningham, Federico Grossi, Joseph C. Banis, Pascal Brouha, Allen Furr, Claudio Maldonado, Osborne Wiggins, Gustavo Perez-Abadia, Cedric François, Barckley Storey, Christopher C. Reynolds, Johannes M. Frank, Moshe Kon, John H. Barker, Investigation of Risk Acceptance in hand transplantation. J Hand Surg, 31A: 295–302. 2006.

John H. Barker, M.D., Ph.D.; Allen Furr, Ph.D.; Michael Cunningham, Ph.D.; Federico V. Grossi, M.D.; Dalibor Vasilic, M.D.; Barckley Storey; Osborne Wiggins, Ph.D.; Pascal Brouha, M.D; Marieke Vossen, M.D.; Ramsey Majzoub, M.D.; Serge Martinez, MD; Claudio Maldonado, Ph.D.; Christopher C. Reynolds; Cedric Francois, M.D., Ph.D.; Gustavo Perez-Abadia, MD; Johannes M. Frank, M.D., Ph.D.; Moshe Kon, M.D., Ph.D.; Joseph C. Banis Jr., M.D. Investigation of Risk Acceptance in Facial Transplantation. Plast Reconstruc Surg, 118(3): 663-670, 2006.

Christopher C Reynolds; Michael Cunningham, PhD; Federico Grossi, MD; Serge A. Martinez, MD, JD; Jeffrey M. Bumpous, MD; Eric J. Lentsch, MD; Joseph C. Banis, MD; Allen Furr, PhD; Dalibor Vasilic, MD; Barckley Storey; Osborne Wiggins, PhD;  Claudio Maldonado, PhD;  Gustavo Perez-Abadia, MD; John H. Barker, MD, PhD.  Risk acceptance in laryngeal transplantation.  Laryngoscope, 2006. Laryngoscope, 116:1770–1775, 2006.

John H. Barker, M.D., Ph.D.; Allen Furr, Ph.D.; Michael Cunningham, Ph.D.; Federico V. Grossi, M.D.; Dalibor Vasilic, M.D.; Barckley Storey; Osborne Wiggins, Ph.D.; Pascal Brouha, M.D; Marieke Vossen, M.D.; Ramsey Majzoub, M.D.; Serge Martinez, MD; Claudio Maldonado, Ph.D.; Christopher C. Reynolds; Cedric Francois, M.D., Ph.D.; Gustavo Perez-Abadia, MD; Johannes M. Frank, M.D., Ph.D.; Moshe Kon, M.D., Ph.D.; Joseph C. Banis Jr., M.D. Investigation of Risk Acceptance in Facial Transplantation. Plast Reconstruc Surg 118(3):663-670, 2006.

Majzoub, RK., Cunningham, M., Grossi, F., Maldonado, C., Banis, JC., & Barker, JH. (2006). Investigation of risk acceptance in hand transplantation. J Hand Surg [Am], 31(2): 295-302.16473694.

Pascal Brouha, Deepak Naidu, Michael Cunningham, Allen Furr, Ramsey Majzoub, Federico V. Grossi, Cedric G. Francois, Claudio Maldonado, Joseph C. Banis, Serge Martinez, Gustavo Perez-Abadia, Osborne Wiggins, Moshe Kon, John H Barker. "Risk Acceptance in Composite Tissue Allotransplantation reconstructive procedures." Microsurgery, 26:3 144-49. 2006.

Banis, JC., JH Barker, M. Cunningham, CG. Francois, A. Furr, F. Grossi, M. Kon, C. Maldonado, S. Martinez, G. Perez-Abadia, M. Vossen, and OP. Wiggins.  Response to Selected Commentaries on the AJOB Target Article "On the Ethics of Facial Transplantation Research."  The American Journal of Bioethics,  4(3): W23-W31, 2004.

Cunningham, M., Majzoub, R,. Brouha, PCR., Laurentin-Perez L., Naidu, DK., Maldonado, C., Banis, JC., Grossi, F., Frank, JM., Barker, JH. Risk acceptance in composite tissue allotransplantation reconstructive procedures: Instrument design and validation European J Trauma, 30:12-16, 2004.

Cunningham, M., & Barker, J. (2004a). Response to A. Clarke, and PEM. Butler, Patient selection for facial transplantation II: Psychological considerations. International Journal of Surgery, 2(2): 117-118. 

Cunningham, M., & Barker, J. (2004b). Response to R. Farrer.  Psychological considerations in face transplantation. International Journal of Surgery 2(2): 78-79.

Furr, L., & Barker, J. (2004). Response to I. Summerton and R. Agha, Sociological considerations in face transplantation. International Journal of Surgery, 2(2): 83.

Wiggins, O., & Barker, J. (2004a). Response to G. Thorburn, S. Hettiaratchy, R. Ashcroft, and P.E.M. Butler, Patient selection for facial transplantation III: Ethical considerations. International Journal of Surgery, 2(2): 119.

Wiggins, O., & Barker, J. (2004b). Response to P Haughton, Ethical considerations of facial transplantation research. International Journal of Surgery, 2(2): 81-82.

Wiggins, OP., Barker, JH., Martinez, S., Vossen, M., Maldonado, C., Grossi, F., et al. (2004). On the ethics of facial transplantation research. Am J Bioeth, 4(3): 1-12.16192123.

Wiggins, OP, Barker, JH,  Martinez, S, Vossen, M, Maldonado, C, Grossi,  F, Francois, CG, Cunningham, M, Perez-Abadia, G, Kon, M, and Banis, JC.  On the Ethics of Facial Transplantation Research.  American Journal of Bioethics, 4(3): 1-12, 2004.

McCabe, S., Rodocker, G., Julliard, K., Breidenbach, W., Marcel, C., Shirbacheh, M. V., et al. (1998). Using decision analysis to aid in the introduction of upper extremity transplantation. Transplant Proc, 30(6): 2783-2786.9745566.

 

Related Work of Others:

Belanger, M., Harris, P. G., Nikolis, A., et al. Comparative analysis between scientific and the media communication following facial transplantation. Transplant Proc 41: 485-488, 2009.

Edgar A. The challenge of transplants to an intersubjectively established sense of personal identity. Health Care Anal. 2009 Jun;17(2):123-33.

Johnson SE, Corsten MJ. Facial transplantation in a new era: what are the ethical implications? Curr Opin Otolaryngol Head Neck Surg. 2009 May 5.

Knobloch K, Rennekampff HO, Vogt PM. Face as an organ: a political dimension in the European Union. Ann Plast Surg. 2009 Mar;62(3):335.

Pomahac B, Aflaki P, Nelson C, Balas B. Evaluation of Appearance Transfer and Persistence in central face transplantation: A computer simulation analysis. J Plast Reconstr Aesthet Surg. 2009 Apr 22.

Grayling, A. C. Face transplantation and living a flourishing life. Lancet 371: 707-708, 2008.

Siemionow, M., Sonmez, E. Face as an organ. Ann Plast Surg 61: 345-352, 2008.

Face transplant pioneer to speak at conference. Br Dent J 205: 116, 2008.

White, B. E., Brassington, I. Facial allograft transplants: where's the catch? J Med Ethics 34: 723-726, 2008.

Ad-El, D. D. On the ethics of composite tissue allotransplantation (facial transplantation). Plast Reconstr Surg 119: 747, 2007.

Clarke, A., Murphy, F., White, P., Brough, V., Renshaw, A., Butler, P. E. Transplant professionals' attitudes toward facial transplantation in the United Kingdom. Prog Transplant 17: 228-233, 2007.

Freeman, M., Abou Jaoude, P. Justifying surgery's last taboo: the ethics of face transplants. J Med Ethics 33: 76-81, 2007.

Hurlburt, M. Facial transplantation: understanding the interests of patients and hurdles to informed consent. Med Sci Monit 13: RA147-153, 2007.

Khan, A. A., Diver, A. J., Clarke, A., Butler, P. E. A mathematical risk-benefit analysis of composite tissue allotransplantation. Transplantation 84: 1384-1390, 2007.

Masquelet, A. C. [Philosophical and ethics aspects of the composite tissues allotransplantations (CTA).]. Ann Chir Plast Esthet, 2007.

Swindell, J. S. Facial allograft transplantation, personal identity and subjectivity. J Med Ethics 33: 449-453, 2007.

Brill, SE., Clarke, A., Veale, D. M., et al. Psychological management and body image issues in facial transplantation  Body Image, 3: 1-15 2006.

Carosella, ED., Pradeu, T. Transplantation and identity: a dangerous split? Lancet, 368: 183-184, 2006.

Clarke, A., Simmons, J., White, P., et al. Attitudes to Face Transplantation: Results of a Public Engagement Exercise at the Royal Society Summer Science Exhibition. J Burn Care Res, 27: 394-398, 2006.

Daly, CC. (2006). Saving face. South Med J, 99(4): 412-413.16634259.

The French position: Comite Consultatif National d'Ethique pour les sciences de la vie et de la sante: "composite tissue allograftransplantation of the face (total or partial graft)". (2006). South Med J, 99(4). 432-433.16634268.

Gaba, A. Face transplants and the difficulties of obtaining research approval. J Biolaw Bus 9: 54-55, 2006.

Hamdy, RC. (2006). Face transplantation: a brave or maverick surgery? South Med J, 99(4): 410-411.16634258.

Hutchison, I. (2006). Face transplants: is the genie out of the bottle? South Med J, 99(4): 427-429.16634265.

Liang, B. A. The bounds of science and ethics. J Biolaw Bus 9: 44-45, 2006.

Lantieri, LA. (2006). Face transplantation: the view from Paris, France. South Med J, 99(4): 421-423.16634263.

Mannan, A., Ghani, S., Clarke, A., et al. Psychosocial outcomes derived from an acid burned population in Bangladesh, and comparison with Western norms. Burns, 32: 235-241, 2006.

Okie, S. (2006). Facial transplantation: brave new face. N Engl J Med, 354(9): 889-894.16510742.

Peled, ZM., & Pribaz, JJ. (2006). Face transplantation: the view from Harvard Medical School. South Med J, 99(4): 414-416.16634260.

Renshaw, A., Clarke, A., Diver, AJ., et al. Informed consent for facial transplantation. Transpl Int ,19: 861-867, 2006.

Shack, B. (2006). Face transplantation: the view from Vanderbilt University. South Med J, 99(4): 419-420.16634262.

Wigmore, SJ. (2006). Face transplantation: the view from Birmingham, England. South Med J, 99(4): 424-426.16634264.

Agich, GJ., & Siemionow, M. (2005). Until they have faces: the ethics of facial allograft transplantation. J Med Ethics, 31(12): 707-709.16319234. 

Clark, PA. (2005b). Face transplantation: Part II-an ethical perspective. Med Sci Monit, 11(2): RA41-47.15668643.

Martin, J. (2005). [Patient satisfaction, measure of the ethical character of medical acts? About the face transplant in Amiens]. Rev Med Suisse, 1(46): 3003.16429978.

Agich, GJ., & Siemionow, M. (2004). Facing the ethical questions in facial transplantation. Am J Bioeth, 4(3), 25-27; discussion W23-31.16192130 .

Ankeny, RA., & Kerridge, I. (2004). On not taking objective risk assessments at face value. Am J Bioeth, 4(3): 35-37; discussion W23-31.16192135.

Baylis, F. (2004). A face is not just like a hand: pace Barker. Am J Bioeth, 4(3). 30-32; discussion W23-31.16192132.

Bosch, X. (2004). Surgeon denied ethics approval for face transplantation. Lancet, 363(9412): 871.15032241.

Caplan, A. (2004). Facing ourselves. Am J Bioeth, 4(3): 18-20; discussion W23-31.16192127

Chambers, T. (2004). How to do things with AJOB: the case of facial transplantation. Am J Bioeth, 4(3): 20-21.16192128.

Check, E. (2004). Surgeons seek go-ahead to perform first face transplant. Nature, 431(7007): 389.15385974.

Farrer, Rob. AFBPS. Psychological Considerations in Face Transplantation. International Journal of Surgery, 2: 2004.

Frank, AW. (2004). Emily's scars. Surgical shapings, technoluxe, and bioethics. Hastings Cent Rep, 34(2): 18-29.15156834.

Full or partial face transplants. (2004). Bull Med Ethics(202): 9-11.15685757.

Goering, S. (2004). Facing the consequences of facial transplantation: individual choices, social effects. Am J Bioeth, 4(3): 37-39; discussion W23-31.16192136.

Haughton, Peter. Ethical Considerations in Face Transplantation. International Journal of Surgery, 2: 2004.

Huxtable R., Woodley J.  Gaining face or losing face?  Framing the debate on face transplants.  Bioethics,  19: 505, Oct. 2004.

Maschke, KJ., & Trump, E. (2004). Facial transplantation research: a need for additional deliberation. Am J Bioeth, 4(3): 33-35; discussion W23-31.16192134.

Miles, SH. (2004). Medical ethicists, human curiosities, and the new media midway. Am J Bioeth, 4(3): 39-43.16192137.

Morreim, EH. (2004). About face: downplaying the role of the press in facial transplantation research. Am J Bioeth, 4(3): 27-29; discussion W23-31.16192131.

Morris, PJ., & Monaco, AP. (2004). Facial transplantation: is the time right? Transplantation, 77(3): 329.

Robertson, JA. (2004). Face transplants: enriching the debate. Am J Bioeth, 4(3): 32-33; discussion W23-31.16192133.

Rumsey, N. (2004). Psychological aspects of face transplantation: read the small print carefully. Am J Bioeth, 4(3): 22-25; discussion W23-31.16192129.

Rumsey, N., Clarke, A., White, P., Wyn-Williams, M., & Garlick, W. (2004). Altered body image: appearance-related concerns of people with visible disfigurement. J Adv Nurs, 48(5): 443-453.15533082.

Strong, C. (2004). Should we be putting a good face on facial transplantation? Am J Bioeth, 4(3): 13-14; discussion W23-31.16192124.

Summerton, and R. Agha. Societal Considerations in Face Transplantation. International Journal of Surgery, 2: 2004.

Thorburn, Guy,  Hettiaratchy, Shehan,  Ashcroft, Richard, Butler Peter E.M. Patient Selection for Facial Transplantation III: Ethical Considerations. International Journal of Surgery, 2: 2004.

Trachtman, H. (2004). Facing the truth: A response to "On the ethics of facial transplantation research" by Wiggins et al. Am J Bioeth, 4(3): W33-34.16192117.

Genden, E. M., Urken, M. L. Laryngeal and tracheal transplantation: ethical limitations. Mt Sinai J Med 70: 163-165, 2003.

Hull, AM., Lowe, T., Devlin, M., Finlay, P., Koppel, D., & Stewart, A. M. (2003). Psychological consequences of maxillofacial trauma: a preliminary study. Br J Oral Maxillofac Surg, 41(5): 317-322.14581024.

Huffman, JC., Popkin, MK., & Stern, TA. (2003). Psychiatric considerations in the patient receiving organ transplantation: a clinical case conference. Gen Hosp Psychiatry, 25(6): 484-491.14706415.

Kmietowicz, Z. (2003). Face transplants should not be done without more research. Bmj, 327(7425): 1184.14630734.

Langone AJ, Helderman JH. Disparity between solid-organ supply and demand. New England Journal of Medicine, 2003; 349: 704-706.

Bohachick, P., Taylor, M. V., Sereika, S., Reeder, S., & Anton, B. B. (2002). Social support, personal control, and psychosocial recovery following heart transplantation. Clin Nurs Res, 11(1). 34-51.11845513.

McDowell, N. (2002). Surgeons struggle with ethical nightmare of face transplants. Nature, 420(6915), 449.12466799

Rothenhausler, H. B., Ehrentraut, S., Kapfhammer, HP., Lang, C., Zachoval, R., Bilzer, M., et al. (2002). Psychiatric and psychosocial outcome of orthotopic liver transplantation. Psychother Psychosom, 71(5): 285-297.12207109.

Alam, M. (2001). Making the Body Beautiful: A Cultural History of Aesthetic Surgery. Arch Dermatol, 137(6):  835. 

Edgell, SE., McCabe, SJ., Breidenbach, WC., Neace, WP., La Joie, AS., Abell, TD. Different reference frames can lead to different hand transplantation decisions by patients and physicians. J Hand Surg [Am], 2001; 26: 196-00.

Martin P. Evison.  Modeling Age, Obesity, and Ethnicity in a Computerized 3-D Facial Reconstruction. Presented at the 9th Biennial Meeting of the International Association for Craniofacial Identification, FBI, Washington, DC, July 2000; Forensic Science Communications 2001; 3.  Available at: www.fbi.gov/hq/lab/fsc/backissu/april2001/evison.htm

Widows, M. R., Jacobsen, P. B., & Fields, K. K. (2000). Relation of psychological vulnerability factors to posttraumatic stress disorder symptomatology in bone marrow transplant recipients. Psychosom Med, 62(6): 873-882.11139008.

Haiken, E. (1999). Venus envy : a history of cosmetic surgery (Johns Hopkins paperbacks ed.). Baltimore: Johns Hopkins University Press.

Klapheke M. Transplantation of the human hand: Psychiatric implications. Bulletin of the Menninger Clinic, 1999; 63: 159-173.

Rudman, L., Gonzales, M., & Borgida, E. (1999). Mishandling the gift of life: Noncompliance in renal transplant patients. Journal of Applied Social Psychology 29(4), 834-851.

Stevenage, S., & McKay, Y. (1999). Model applicants: The effect of facial appearance on recruitment decisions. British Journal of Psychology, 90: 221-234.

Woodman, CL., Geist, LJ., Vance, S., Laxson, C., Jones, K., & Kline, JN. (1999). Psychiatric disorders and survival after lung transplantation. Psychosomatics, 40(4):  293-297.10402873.

Rush, D., Nickerson, P., Gough, J., McKenna, R., Grimm, P., Cheang, M., et al. (1998). Beneficial effects of treatment of early subclinical rejection: a randomized study. J Am Soc Nephrol, 9(11): 2129-2134.9808101.

Siegler M. Ethical issues in innovative surgery: Should we attempt a cadaveric hand transplantation in a human subject? Transplantation Proceedings, 1998; 30: 2779-82.

Yates, WR., LaBrecque, DR., & Pfab, D. (1998). Personality disorder as a contraindication for liver transplantation in alcoholic cirrhosis. Psychosomatics, 39(6): 501-511.9819950.

Broers, S., Hengeveld, MW., Kaptein, AA., Le Cessie, S., van de Loo, F., & de Vries, T. (1998). Are pretransplant psychological variables related to survival after bone marrow transplantation? A prospective study of 123 consecutive patients. J Psychosom Res, 45(4): 341-351.9794280.

Bruce V. and Young A. In: In the eye of the beholder: The science of face perception. Whose face is it? How individual faces are recognized. Chapter 5. Oxford: Oxford U. Press 1998.

Ye EM. Psychological morbidity in patients with facial and neck burns. Burns, 1998; 24: 646-48.

Walters, E. (1997). Psychological research on visible difference in adults: Butterworth Heinemann, London.

Robinson, E. (1997). Psychological research on visible difference in adults: Butterworth Heinemann, London.

Robinson E., Rumsey N. and Partridge J. An evaluation of the impact of social interaction skills training for facially disfigured people. Br J Plast Surg 1996; 49: 281-289.

Grealy L. Autobiography of a face. HarperCollins Publishers, Inc. 1995.

Olbrisch, ME., & Levenson, JL. (1995). Psychosocial assessment of organ transplant candidates. Current status of methodological and philosophical issues. Psychosomatics, 36(3): 236-243.7638310.

Houston, V., & Bull, R. (1994). Do people avoid sitting next to someone who is facially disfigured? European Journal of social Psychology, 24(2): 279-284.

Jenkins, PL., Lester, H., Alexander, J., & Whittaker, J. (1994). A prospective study of psychosocial morbidity in adult bone marrow transplant recipients. Psychosomatics, 35(4): 361-367.8084987.

Stuber, M. L. (1993). Psychiatric aspects of organ transplantation in children and adolescents. Psychosomatics, 34(5): 379-387.8140186.

Pruzinsky, T. (1992). Social and psychological effects of major craniofacial deformity. Cleft Palate Craniofac J, 29(6): 578-584; discussion 570.1450200.

Colon, EA., Callies, A. L., Popkin, M. K., & McGlave, P. B. (1991). Depressed mood and other variables related to bone marrow transplantation survival in acute leukemia. Psychosomatics, 32(4): 420-425.1961856.

Doukas, DJ., & McCullough, LB. (1991). The values history. The evaluation of the patient's values and advance directives. J Fam Pract, 32(2): 145-153.1990042.

Macgregor FC. Facial Disfigurement: Problems and management of social interaction and implications for mental health. Aesthetic Plastic Surgery, 1990; 14: 249-257.

Moore FD. Transplantation Proceedings , 1988; 20(1; Supplement): 1061-1067.

Childress, JF. The gift of life. Ethical problems and policies in obtaining and distributing organs for transplantation. Crit Care Clin, 1986; 2: 133-148.

Goin, M. K., & Goin, J. M. (1986). Psychological effects of aesthetic facial surgery. Adv Psychosom Med, 15: 84-108.3706039.

Rumsey, N., & Bull, R. (1986). The effects of facial disfigurement on social interaction. Human Learning, 5: 203-208.

Lefebvre A. and Barclay S. Psychosocial impact of craniofacial deformities before and after reconstructive surgery. Can J Psychiatry, 1982; 27: 579-583.

Rumsey, N., Bull, R., & Gahagan, D. (1982). The effect of facial disfigurement on the proxemic behavior of the general public. Journal of Applied Social Psychology, 12(2): 137-150.

Bull, R., & Stevens, J. (1981). The effects of facial disfigurement on helping behaviour. Italian Journal of Psychology, 111: 25-33.

Langer, E., Fiske, S., Taylor, S., & al., e. (1976). Stigma, staring and discomfort:A novel-stimulus analysis. Journal of Experimental Social Psychology, 12: 451-463.

 

 

Lay Publications

 

Related Work of Others:

 

2008

Coombes, R. Face of the future. Bmj 336: 18-19, 2008.

2007

Glicenstein, J. [Allotransplantations, literature and movie.]. Ann Chir Plast Esthet, 2007.

2006

Bernard, A., & Smith, C. (2006). French Face-Transplant Patient Tells of Her Ordeal Retrieved May 3, 2006, from http://www.nytimes.com/2006/02/07/international/europe/07face.html?ex=1296968400&en=575210c9428d7970&ei=5088&partner=rssnyt&emc=rss 

China's 1st face transplant successful. (2006).   Retrieved April 15, 2006, from http://news.xinhuanet.com/english/2006-04/14/content_4425653.htm

Ethics of the Face Transplant: Focus on the Positive (2006).   Retrieved May 3, 2006, from http://query.nytimes.com/gst/fullpage.html?res=9B01EFD71131F932A25751C1A9639C8B63

Facial Transplantation ASRM/ASPS Guiding Principles. (2006). from http://www.microsurg.org/ftGuidelines.pdf 

The UK Face Transplant Information Website. (2006).   Retrieved March 15, 2006, from http://www.facialtransplantation.org.uk/content/info2.asp 

Facial transplant surgery arrives in America. (2006).   Retrieved April 29, 2006, from http://www.beautynova.com/blog/?m=200601 

Parker, Q. (2006). TALKING SCIENCE - THE 24 HOUR MUSEUM GOES TO THE DANA CENTRE.   Retrieved March 17, 2006, from http://www.24hourmuseum.org.uk/nwh_gfx_en/ART18716.html 

Online, PSD. (2005, April 3, 2006). 11-year-old Chinese girl may undergo face transplant. from http://english.people.com.cn/200512/27/eng20051227_231166.html  

Smith, R. (2005). THE WORLD'S FIRST FACE TRANSPLANT. Evening Standard (London),   http://www.findarticles.com/p/articles/mi_qn4153/is_20051130/ai_n15868923.  Retrieved April 28, 2006, from http://www.findarticles.com/p/articles/mi_qn4153/is_20051130/ai_n15868923

Doctors searching for the facial transplantant patient and donor. (2004).   Retrieved March 17, 2006, from http://newsfromrussia.com/science/2004/11/02/56918.html 

Pascale, C. (2004). Cleveland Clinic board approves facial transplant procedure.   Retrieved March 17, 2006, from http://www.thetartan.org/2004/11/8/scitech/clevelandclinicboardapprovesfacialtransplantproced 

Dougherty, H. (2003). Burns girl to have first face transplant Retrieved April 26, 2006, from http://www.thisislondon.com/news/articles/3609267?source=Evening%20Standard 

Lena Marie Murphy: apology (2003).   Retrieved April 26, 2006, from http://www.unison.ie/irish_independent/stories.php3?ca=9&si=928546&issue_id=8841 

Bhattacharya, S. (2003). First human tongue transplant successful.   Retrieved April 29, 2006, from http://www.newscientist.com/article.ns?id=dn3964 

Concar, D. (1998). Hands today, faces tomorrow.   Retrieved March 17, 2006, from http://www.newscientist.com/article/mg16021542.000.html

2005

Altman, LK. (2005a). French, in first, use a transplant to repair a face. NY Times (Print), A1, A6.16450461 

Altman, LK. (2005b). A pioneering transplant, and now an ethical storm. NY Times (Print), FL; F4.16342443 

Cleveland Clinic IRB gives ok to Dr. Siemionow to do face transplant. (2005). from http://www.allbusiness.com/periodicals/article/600385-1.html 

Gorman, C. (2005). A transplant first. Time, 166(24), 58.16350780 

Mason, M., & Altman, LK. (2005). Ethical concerns on face transplants grow; American scientists raise medical and psychological issues. NY Times (Print), A12.16342446 

Springen, K. (2005). Health for life. The ultimate transplant. Newsweek, 146(24), 60-61.16375165

Smith, C. S. (2005a). As a face transplant heals, flurries of questions arise; doctors differ on ethics and patient's mental state. NY Times (Print), A1, A14.16453396 

Smith, C. S. (2005b). Dire wounds, a new face, and glimpse in a mirror. NY Times (Print), A1, A8.16342440. 

2004

Cleveland Clinic first to gain approval to perform human face transplant. (2004). from http://www.allbusiness.com/periodicals/article/347405-1.html 

The Face as Frontier.  Los Angeles Times, Special Weekend Section,  February 2nd, 2004.

How to Replace a Face. New Scientist,  May 27th, 2004. 

Surgeon denied ethics approval for face transplantation. Lancet, March. 13: 363(9412): 871. 2004.

Trump, EF., & Maschke, K. (2004). A stranger in the mirror: should doctors transplant faces? NY Times (Print), F5.15487063.

2003

Surgeons warn about risk of face transplant. The Daily Telegraph Newspaper ,(UK), interview, November 20th, 2003.  

Surgeons urge research into face transplant. Financial Times Newspaper, (UK), interview, November 20th 2003.

Surgeons warn of face transplant race. The Guardian Newspaper,(UK), interview, November 20th, 2003. 

Surgeons in two minds over face transplant. The Times Newspaper,(UK), interview, November 20th, 2003.

2000

Franken Science push back the frontiers of medicine. London Sunday Times Magazine, February 6, 2000, pp. 43-56.

1999

Gaining Face. Salon.com - Health & Body, May 19th, 1999.

New direction for transplants raises hopes and questions. New York Times, May 2, 1999.

1998

Doctors who transplanted hand ponder their surprising patient. New York Times, October 6, 1998, p. B11. 

Medical innovation close at hand. American Medical News, September 14, 1998, p.1.

Surgeons in France try hand transplant. New York Times, September 25, 1998.

Medische dorbraac, ethisch dilemma. De  Standard (Belgium), September 28, 1998.

If the face doesn’t fit, then get a new one. Sydney Morning Herald, October 1, 1998.  

Frankenstein moving from fiction to fact. The Globe and Mail, November 5, 1998. 

Hand surgeons decry French transplant as much too risky. Physician’s Weekly, November 8, 1998, p.1. 

 

Scientific and Lay Presentations

Our Work:

ADDIN EN.REFLIST BAPRAS. BAPRAS response to news of British face transplantation go-ahead.  2006  [cited November 9, 2006]; Available from: http://www.bapras.org.uk/UploadFiles/BAPRAS%20Response%20Face%20Transplant.pdf

Dawn Fratangelo, 'Facing' the future of transplants.  Dateline NBC  MSNBC.  January 18, 2004.

Facial Transplantation Radio National ‘Breakfast Australia’s leading news and current affairs program  broadcasting in Australia and the rest of the Asia-Pacific. February, 10th 2004. 

Face Transplantation Dateline NBC News interview aired January 19th, 2004. 

Face Transplantation Radio Caracol Columbia news program  broadcasting throughout Latin America, live interview. February 18th, 2004.

Face Transplantation BBC International Ecuador, Live interview aired June 3rd 2003.

Barker, J. Naked Science – Face of the Future, Public Debate on the Feasibility of Face Transplantation. In Public Debate on the Feasibility of Face Transplantation, London Science Museum, Dana Center. London, UK, November 19th 2003, 2003.; Available from:  http://www.danacentre.org.uk/events/2003/11/19/21

Trasplantación de Cara, Es Posible? Radio National de Costa Rica, Live interview aired May 15th 2003.

Vossen, M,, Molfese. DL,, Fonaryova-Key, A., Kelly, S., Maldonado, C., Kon, M., Barker, JH. Brain plasticity following hand transplantation. Annual Meeting of the Society for University Surgeons, Houston, TX. February 2003.*

Barker, JH. “Composite tissue allotransplantation for reconstructing complex tissue defects: On the frontier of reconstructive surgery” Klinikum der Johann Wolfgang Goethe-Universitat Frankfurt am Main, Aspekte der Rekonstruktiven und Plastischen Chirurgie nach Verletzungen. Frankfurt, Germany April 24th 2002.

Barker, JH. “Composite tissue allotransplantation research collaboration between the Universities of Louisville and Utrecht” Grand Rounds, University Hospital, Utrecht, The Netherlands. April 22nd 2002. 

Barker, JH. “Past and Future Research; the foundation for clinical composite tissue allotransplantation”. Annual meeting of the Dutch Society of Hand, Reconstructive and Aesthetic Surgery, Belhaven, NL, 4-5-2002.

Banis, JC, Brouha, PCR., Majzoub, RK., Stadelmann, WK., Cunningham, M., Maldonado, C., Kon, M., Barker, JH. How much risk are individuals willing to accept to receive composite tissue allotransplantation reconstructive procedures? Annual Meeting of the American Association of Plastic Surgery, April 2002, Seattle, Washington.

Hand transplantation, the future is here Radio Health Journal, Aired the week of October 20, 2002.

Vossen, M., Molfese, DL., Fonaryova-Key, A., Kelly, S., Maldonado, C., Kon, M., Barker, JH. Brain plasticity following hand transplantation. 37th Congress of the European Society for Surgical Research, Szeged, Hungary. 23-25 May 2002 .

Vossen ,M., Molfese, DL., Fonaryova-Key, A., Maldonado, C., Kon, M., Barker, JH. Cortical reorganization following hand transplantation. 13th Annual meeting of the European Association of Plastic Surgeons, Crete, Greece. 30 May-1 June 2002.

Orhun ,H., Gorantla, V., Voor, M., Breidenbach, W., Barker, JH. Elastic properties of bone in composite tissue allografts. 8th Congress of the International Federation of Societies for Surgery of the Hand (IFSSH), Istanbul, Turkey, June 10-14, 2001.

Barker, JH. Animal research leading to the nation’s first human hand transplant. 2nd International Symposium on Composite Tissue Allograft. Louisville, KY, May 18-19, 2000.

Barker, J, Breidenbach W, Jones J, Shirbacheh MV. Potential benefit of local immunotherapy in hand transplantation. 54th Annual Meeting of the American Society for Surgery of the Hand, Boston, MA, September 2-4, 1999.

Jones, JW., Breidenbach WC, Barker JH, Gruber SA. From bench to bedside: porcine extremity composite tissue allograft (CTA) to human hand transplant. American Society of Transplantation Surgeons, 18th annual Meeting, Chicago IL, May 15-19, 1999.

Jones, JW., Zdichavsky, M., Ustuner, ET., Ren, XP., Edelstein, J., Maldonado, C., Jevans, A., Ray, M., Breidenbach, WC., Barker, JH., Gruber, SA. Dep. Long-term composite tissue allograft (CTA) survival in a pig model with FK506 (FK/mycophenolate mofetil (MMF) Therapy. 60th Annual Meeting of the Society of University Surgeons, New Orleans, LA, February 11-13, 1999.

Zdichavsky, M., Jones, JW., Ustuner, T., Ren, X., Edelstein, J., Maldonado, C., Breidenbach, W., Barker, JH., Ray, M. Assessment of skin rejection in composite tissue allografts (CTA) by a histological grading system in a swine model. United States and Canadian Academy of Pathology, Inc., (USCAP) Annual Meeting,  San  Francisco, CA,  March 20-26, 1999.

Zdichavsky, M., Ustuner, T., Jones, JW., Edelstein, J., Breidenbach, W,, Jevans, A., Maldonado, C., Barker, JH. Cyclosporine A combination therapy prolongs composite tissue allograft survival in a swine model. 34th Congress of the European Society of Surgical Research (ESSR), Bern, Switzerland, April 22-24, 1999.

A chat with a hand surgeon. CNN Health Chat line, January 29, 1998.

Dana Center Discussions, Medicine, Face of the future… Available at: http://193.62.111.15/default.aspx?DanaAction=ShowPost&PostID=68

Ren, X., Zdichavsky, M., Ustuner, ET., Harralson, TG., Jones, JW., Breidenbach, WC., Marzi, I., Maldonado, C., Barker. JH. Radial forelimb osteomyocutaneous flap as a composite tissue allotransplant model in swine.  Plastic Surgery Research Council Annual Meeting, Loma Linda, CA, April 4-7, 1998.

Shirbacheh, S., Breidenbach WC, Barker JH. The feasibility of human hand transplantation. Seventh IFSSH Congress, Vancouver, BC, May 24-28, 1998.

Rodocker, G., McCabe, SJ., Breidenbach, WC., Barker, JH., et, al. Evaluating the feasibility of upper extremity transplantation using decision analysis. Seventh IFSSH Congress, Vancouver, BC, May 24-28, 1998.

The world’s first hand transplant”. Evening Standard (London, Eng), September 24, 1998.

 
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